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Ralph L. Henry Office: SCEN 530 Phone: 575-2529 rahenry@uark.edu

Degrees:

Ph.D. Kansas State University, 1991

Research Interests:

Research in the Henry laboratory is aimed at using molecular and biochemical tools to:

1. Understand how proteins are delivered from their site of synthesis in the cell to their functional location within cellular organelles (Protein Targeting & Protein Transport Across Cell Membranes). Funding for this work comes from the National Institutes of Health and the Department of Energy. This project is being conducted in collaboration with Dr. Suresh Kumar and Dr. Robyn Goforth (UAF).
2. Develop protein expression and purification systems for the production of therapeutic proteins to be used for the treatment of drug abuse, e.g. methamphetamine abuse. Funding for this research comes from the National Institutes of Health/National Institute of Drug Abuse. This project is being conducted in collaboration with Dr. Joshua Sakon (UAF), Dr. Mike Owens, and Dr. Brooks Gentry (UA for Medical Sciences).

Academic Interests:

Protein targeting and transport in chloroplasts and other membrane systems.

Lab Website:

Click here to go to Dr. Henry's lab website.

Recent Publications:

Henry R., R.L. Goforth, D. Schunemann. 2007. Chloroplast SRP/FtsY and Alb3 in protein integration into the thylakoid membrane. The Enzymes 25, in press.

Tzvetkova-Chevolleau T., C. Hutin, L. D. Noel, R. Goforth, J. P. Carde, S. Caffarri, I. Sinning, M. Groves, J. M. Teulon, N. E. Hoffman, R. Henry, M. Havaux and L. Nussaume. 2007. Canonical signal recognition particle components can be bypassed for posttranslational protein targeting in chloroplasts. Plant Cell 19(5):1635-1648.

Peterson E. C., M. Gunnell, Y. Che, R. L. Goforth, F. Ivy Carroll, R. Henry, H. Liu and S. M. Owens. 2007. Monoclonal antibody medications discovery for methamphetamine-like drugs by hapten design. J. Pharmacology and Exp. Therapeutics 322(1):30-39.

Peterson E. C., S. M. Owens, R.L. Henry. 2006. Monoclonal antibody form and function: manufacturing the right antibodies for treating drug abuse. AAPS Journal 8(2):E383-390.

Sivaraja, V., T.K.S. Kumar, P.S.T. Leena, A. Chang, C. Vidya, R.L. Goforth, D. Rajalingam, K. Arvind, J. Ye, J. Chou, R. Henry and C. Yu. 2005. Three-dimensional solution structures of the chromo domains of cpSRP43. J. Biol Chem. 280(50):41465-71.